از سری کتاب های آموزشی پزشکی برای دانشجویان پزشکی و متخصصین پاتولوژی (آسیب شناسی)و علوم آزمایشگاهی
From Melanocytes to Melanoma: The Progression to Malignancy (Hardcover)
by Vincent J. Hearing (Editor), Stanley P. L. Leong (Editor) "The neural crest cells initially form as the neural tube is closing: at 8 d of gestation in mice and at 22 d in humans..." (more)
Key Phrases: Biol Chem, Invest Dermatol, Pigment Cell Res (more...)


Review

From the reviews:

"...this compendium of current thinking is recommended reading for anyone with an interest in pigmentation and cancer and a valuable resource for any library." -Melanoma Research

"This book, the first of its kind on melanoma, details the current state of our knowledge . should be viewed as an important resource for understanding the broad field of melanocyte and melanoma biology. Newcomers to the field will find this book extremely useful. This book captures the tremendous progress made in the field . It is a valuable resource for biologists and basic scientists as well as for pathologists; dermatologists, surgeons, and medical oncologists ." (Lynn M. Schuchter, The New England Journal of Medicine, March, 2007)

"...captures the tremendous progress made in the field...will help to propel the field to new successes...a valuable resource for biologists and basic scientists interested in the biology of pigment cells as well as for pathologists, dermatologists, surgeons, and medical oncologists interested in the diagnosis and treatment of melanoma." -New England Journal of Medicine

"The editors have compiled a highly prestigious group of authors, who are leaders in the field of melanocyte and melanoma research, to present a very comprehensive exposition of the current knowledge of melanocyte biology and melanoma. As a clinical researcher, I found it fascinating, yielding a tremendous appreciation for the meticulous and extensive work that has been done to date, some of which has and more of which will very likely provide leads to clinical interventions." (Janice P. Dutcher, Medical Oncology, Vol. 23 (3), 2006)


Product Description
Leading researchers and clinicians join forces to explain how malignant melanoma develops from its benign precursor cell type. The authors focus on the molecular mechanisms involved in melanogenesis, in the malignant transformation of melanocytes, and in the further progression of primary melanomas into invasive and metastatic melanomas. They also review recent advances in our understanding of the basic biology of melanocytes and the development, migration, and differentiation of melanoblasts into melanocytes. The book provides an up-to-date understanding of the progressive mechanisms of oncological development in malignant melanoma, a likely model of malignant progress for other types of cancer, and the ongoing development of novel therapeutics.
Product Details

* Hardcover: 696 pages
* Publisher: Humana Press; 1 edition (December 15, 2005)
* Language: English
* ISBN-10: 1588294595
* ISBN-13: 978-1588294593